Chronic pain affects 20% of the population and one third suffers neuropathic pain, which is an intractable form of pain . Neuropathic pain is defined as persistent pain associated with injury, pathological changes or disease of the somatosensory nervous system. The damage to the nervous system may result from an accident or surgery, even benign surgery or from illnesses such as diabetes, after stroke or during chemotherapy treatment. However, the mechanisms that turn a relatively mild lesion into a severe disability with dramatic individual and socio-economic consequences remain unclear. Understanding these mechanisms is a major goal towards the development of new therapeutic strategies to prevent neuropathic pain. Our fundamental questions, aim to identify the underlying molecular and structural modifications of the nervous system in neuropathic pain using experimental pain models and combining genetic, electrophysiological, optogenetic and behavioral approaches.
Our research laboratory, integral part of the Pain Center of the CHUV, also contributes to the education and training. He welcomes and form the students of the Schools of the Faculty of biology and the medicine, in Master’s degree or of the program Summer Undergraduate Research (SUR) or tof the School of Laborant ESSanté.